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Research Scientist Resume

An academic CV for a biomedical PI showcasing NIH grants, CRISPR genomics research, Nature publications, and a Pew Scholars Award.

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Dr. Kenji Tanaka

Research Scientist | Computational Biology · Genomics · Drug Discovery

Research Summary

Independent research scientist and principal investigator studying the genetic basis of rare metabolic disorders. Published 28 peer-reviewed papers (h-index 18) and secured $4.2M in NIH and NSF grant funding. Expert in single-cell RNA sequencing, CRISPR-Cas9 functional genomics, and computational pathway analysis. Passionate about translating bench discoveries into therapeutic leads.

Research Experience

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The Scripps Research InstituteSeptember 2021 to Present
Assistant Professor & Principal Investigator · San Diego, CA
  • Lead an 8-person lab (3 postdocs, 3 PhD students, 2 research assistants) investigating the genomic and metabolic underpinnings of lysosomal storage disorders.

  • Developed a CRISPR base-editing approach that corrected the target mutation in 78% of patient-derived iPSCs in vitro.

  • Secured $4.2M in grant funding across NIH R01, NSF CAREER, and Pew Biomedical Scholar awards.

  • Published 12 papers since joining Scripps; 4 in Nature/Cell family journals.

Scripps Research
2021
Broad Institute of MIT & HarvardSeptember 2018 to August 2021
Postdoctoral Associate · Cambridge, MA
  • Applied single-cell RNA-seq (10x Genomics) to profile transcriptomic heterogeneity in 15 rare disease patient cohorts.

  • Co-developed an open-source computational pipeline (PyScArches) for integrating multi-modal single-cell data; 1,200+ GitHub stars.

  • Co-first author on Nature Methods paper that became a top-10 cited paper of 2020.

Broad Institute

Education

2021
MIT2018 to 2021
Postdoctoral Fellow — Computational Biology, Cambridge, MA · Advisor: Prof. Eric Lander
2018
Stanford University2013 to 2018
Ph.D. Biochemistry, Stanford, CA · NSF Graduate Research Fellow
2013
University of Tokyo2009 to 2013
B.S. Chemistry, Tokyo, Japan · Summa Cum Laude

Selected Publications

"CRISPR Base Editing Rescues Pathogenic Variants in Lysosomal Biogenesis"2023
Nature Medicine

Demonstrated therapeutic correction of TFEB mutations in patient iPSC-derived hepatocytes using adenine base editors, achieving 78% editing efficiency.

Read Paper
"PyScArches: Scalable Multi-Modal Single-Cell Integration"2020
Nature Methods

Open-source Python toolkit enabling integration of 10M+ cells across scRNA-seq, scATAC-seq, and spatial transcriptomics modalities.

Read Paper

Profiles

Technical Skills

ExperimentalExpert

CRISPR-Cas9, scRNA-seq, iPSC Culture, Flow Cytometry, Western Blot, qPCR

ComputationalAdvanced

Python, R, Seurat, Scanpy, DESeq2, Nextflow

Grant WritingAdvanced

NIH R01, NSF CAREER, Aims Page Development, Budget Justification

Training & Credentials

NIH Principles of Clinical Pharmacology2020
NIH / FAES
Responsible Conduct of Research (RCR) Certified2022
CITI Program

Grants & Honours

NIH R01 Grant — $2.1M2022–2027
National Institutes of Health
Investigating CRISPR-based therapeutic strategies for inherited metabolic disorders.
Pew Biomedical Scholar Award2021
Pew Charitable Trusts
Four-year $300K award for early-career biomedical researchers of exceptional promise.
Harold M. Weintraub Award2019
Fred Hutchinson Cancer Center
Recognises outstanding PhD research in biological sciences.

Service & Mentorship

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Cell & Molecular Biology Graduate Programme2022 to Present
Admissions Committee Member · Scripps Research

Review applications and interview candidates for the CMBB doctoral programme.

Interests

Science Communication

Public Lectures, Science Twitter

Origami

Mathematical Origami, Modular Structures

Languages

EnglishFluent
JapaneseNative

Resume Breakdown

Research Summary

Independent research scientist and principal investigator studying the genetic basis of rare metabolic disorders. Published 28 peer-reviewed papers (h-index 18) and secured $4.2M in NIH and NSF grant funding. Expert in single-cell RNA sequencing, CRISPR-Cas9 functional genomics, and computational pathway analysis. Passionate about translating bench discoveries into therapeutic leads.

Research Experience

Assistant Professor & Principal Investigator

The Scripps Research Institute

September 2021 to Present · San Diego, CA

  • Lead an 8-person lab (3 postdocs, 3 PhD students, 2 research assistants) investigating the genomic and metabolic underpinnings of lysosomal storage disorders.

  • Developed a CRISPR base-editing approach that corrected the target mutation in 78% of patient-derived iPSCs in vitro.

  • Secured $4.2M in grant funding across NIH R01, NSF CAREER, and Pew Biomedical Scholar awards.

  • Published 12 papers since joining Scripps; 4 in Nature/Cell family journals.

Postdoctoral Associate

Broad Institute of MIT & Harvard

September 2018 to August 2021 · Cambridge, MA

  • Applied single-cell RNA-seq (10x Genomics) to profile transcriptomic heterogeneity in 15 rare disease patient cohorts.

  • Co-developed an open-source computational pipeline (PyScArches) for integrating multi-modal single-cell data; 1,200+ GitHub stars.

  • Co-first author on Nature Methods paper that became a top-10 cited paper of 2020.

Education

Postdoctoral Fellow — Computational Biology

MIT

2018 to 2021 · Advisor: Prof. Eric Lander

Ph.D. Biochemistry

Stanford University

2013 to 2018 · NSF Graduate Research Fellow

B.S. Chemistry

University of Tokyo

2009 to 2013 · Summa Cum Laude

Training & Credentials

NIH Principles of Clinical Pharmacology

NIH / FAES · 2020

Responsible Conduct of Research (RCR) Certified

CITI Program · 2022

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